Liudmila Popova

Liudmila Popova

Liudmila Popova

Advisor: Mark Parthun

popova.4@osu.edu

220 Rightmire Hall
1060 Carmack Rd
Columbus, OH 43210

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Areas of Expertise

  • Bioinformatics
  • Cell Biology

Research Description:
Histone acetyltransferase 1 (Hat1) is an enzyme known to acetylate Lysines 5 and 12 on the tail of the newly synthesized histone H4 during the process of replication-coupled chromatin assembly. In an attempt to learn more about the function of Hat1 and potentially identify other acetylation targets, I am focused on utilizing APEX2-based proximity labeling technique to find proteins that are in vivo proximal to Hat1.

Publications:
Nagarajan P , Agudelo Garcia PA , Iyer CC , Popova LV , Arnold WD , Parthun MR (2019). Early-onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1). Aging Cell, e12992. doi: 10.1111/acel.12992.

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