Annika Chura

Annika Chura

Annika Chura

Advisor: Bradley Blaser

chura.5@buckeyemail.osu.edu

Wiseman Hall 424

Areas of Expertise

  • Hematopoietic stem cells
  • Hematopoietic niche

Education

  • BA: Case Western Reserve University

I study mechanisms that influence Hematopoietic Stem Cell (HSC) clonal evolution and lineage commitment. 

Using the zebrafish as a model, we incorporate techniques such as CRISPR gene editing, genetic barcoding, live cell imaging, and single cell genomics and epigenomics.
Understanding the determinants of HSC fate requires elucidating the interplay between intrinsic genetic programs and interactions with the hematopoietic microenvironment. Understanding mechanisms governing HSC fate could lead to improvements in treatment for HSC-associated disorders, including acute myeloid leukemia.