Cytotoxic T lymphocytes are our most important defense against tumors or virus infections. Our lab focuses on understanding how T cell immune responses are generated and maintained during infections and cancer. We are particularly interested in 1) Elucidating mechanisms that regulate de novo epigenetic programming of T cells during infections and cancer; 2) Discovery of novel therapeutic targets to epigenetically reprogram T cells for treating chronic virus infections and cancer using T cell immunotherapies.  

Ghoneim Lab website