My research aims to better understand and treat the maladaptive immune response after spinal cord injury. This is composed of i) the systemic spinal cord injury-induced immune deficiency syndrome (SCI-IDS), ii) consecutive infections and ii) the developing post-traumatic autoimmunity. Both maladaptive neuro-immunological syndromes and their consequences are contributing to the underlying neuropathology and represent a candidate target to improve neurological recovery.