Stephanie Seveau

Stephanie Seveau

Stephanie Seveau

Associate Professor, Microbiology

seveau.1@osu.edu

(614) 247-7674

290 Aronoff
318 W 12th Ave
Columbus, OH
43210

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Areas of Expertise

  • Cell Biology

Education

  • PhD: Pierre and Marie Curie University
My lab studies the molecular mechanisms underlying host-pathogen interactions using Listeria monocytogenes as a model facultative intracellular pathogen.
Specific projects are to:
(1) Establish the L. monocytogenes intracellular life cycle in various mammalian cell types, including human primary placental cells and professional phagocytic cells.
(2) Determine the molecular basis and outcomes of host-cell signaling in response to listeriolysin O, the major virulence factor of L. monocytogenes and a member of the cholesterol-dependent cytolysin (CDC) toxins.
(3) Elucidate the mechanisms underlying the anti-toxin and immunomodulatory activities of antimicrobial peptides that belong to the defensin family.

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