Dr. Bryan R. Smith is a nanomaterials bioengineer and Professor in The Ohio State University's Department of Molecular Medicine and Therapeutics in the College of Medicine. He was recruited from Stanford University to Michigan State University’s Department of Biomedical Engineering, where his lab leveraged an interdisciplinary blend of engineering, imaging, chemistry, biology, physics, and medicine to develop and exploit new imaging and therapeutic approaches. As OSU, Dr. Smith is developing new nanotechnology-based strategies to harness the power of the immune system to diagnose and treat disease. creating novel diagnostic imaging and therapeutic technologies for living subjects. Indeed, major thrusts of the lab include “nano-immunoimaging” and “nano-immunotherapy”, which involve the use of nanoparticles to selectively target immune cells, visualize inflammation or disease processes in vivo, and deliver drugs with high precision while minimizing side effects. Other projects in the lab range from in vivo imaging of cellular mechanical properties to drug release monitoring and biomaterials development. His Translational NanoImmunoEngineering (T-NIE) laboratory places particular emphasis on inflammatory conditions, primarily including cancer, atherosclerosis, and diabetes.