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Dr. Phil Zamore has been an Investigator of the Howard Hughes Medical Institute since 2008. Dr. Zamore is Chair of the RNA Therapeutics Institute, which was established at the University of Massachusetts Chan Medical School in 2009. Dr. Zamore became the Gretchen Stone Cook Professor of Biomedical Sciences in 2005.
Dr. Zamore’s laboratory studies small RNA silencing pathways in eukaryotes and prokaryotes, including RNA interference (RNAi), microRNA, and PIWI-interacting RNA pathways. Dr. Zamore and his collaborators seek to use these insights to design therapies for human diseases, including Huntington’s disease. Under Dr. Zamore’s mentorship, the Zamore Lab has produced dozens of researchers working at top institutions both in the United States and abroad.