
Mary Kate McCulloch
Advisor: Afrooz Rashnonejad
mcculloch.68@buckeyemail.osu.edu
Nationwide Children's Hospital, Abigail Wexner Research Institute, RB4-WC3580
Areas of Expertise
- Gene expression
- Molecular medicine
- Molecular neurobiology
Education
- BS: Ohio University
MK is a PhD student focused on developing AAV-based gene therapies for rare neurodegenerative and neuromuscular diseases, with a primary focus on Charcot-Marie-Tooth disease type 1B (CMT1B). Her work involves designing therapeutics that combine RNA interference and gene replacement strategies, and testing their efficacy both in vitro and in vivo. Additionally, she is developing a CMT1B peripheral nervous system (PNS) organoid model using patient-derived induced pluripotent stem cells (iPSCs).